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Research

Developing sensitive endpoints for respiratory disease progression in children with neuromuscular disease

We hope that through earlier diagnosis and treatment of muscle weakness during sleep, we can prevent future lung failure in children with neuromuscular disorders.

Research

Development and Validation of a Beliefs and Concerns about Screentime Scale

Australian children aged 5 years and younger are exposed to more screen time (e.g., televisions, tables, and smartphones) than ever before.

Research

Development of a universal aftercare model for people who have presented to the emergency department for a suicidal crisis in WA

The Mental Health Commission (MHC) of Western Australia has provided funding to The Kids Research Institute Australia to undertake exploratory research to inform a WA approach to aftercare.

Research

Development of new preclinical models of childhood leukaemia

Sébastien Laurence Rishi S. Malinge Cheung Kotecha PhD BPharm (Hons) MBA PhD MB ChB (Hons) MRCPCH FRACP PhD Laboratory Head, Translational Genomics

Who is involved

The project represents an innovative collaboration between researchers, primarily based at The Kids Research Institute Australia, and 10 government jurisdictions in WA.

Research

Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children

We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.

Research

Intellectual disability: Population-based estimates of the proportion attributable to maternal alcohol use disorder during pregnancy

The aim of this study was to examine the association between maternal alcohol use disorder and intellectual disability in children.

Research

Tertiary paediatric refugee health clinic in Western Australia: Analysis of the first 1026 children

The aim of this study is to describe the epidemiology of common conditions in resettled paediatric refugees attending a tertiary multidisciplinary RHC.

Research

MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63

We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis.