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Research

Does somatosensation change with age in children and adolescents? A systematic review

How different somatosensory modalities develop across childhood into adolescence to use as a point of reference for children at risk of somatosensory

Research

Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

Recruitment of large numbers of pediatric pneumonia and meningitis cases and community controls in a third-world setting presents unique challenges

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Otitis-prone children produce functional antibodies to pneumolysin and pneumococcal polysaccharides

The production of functional antipneumococcal antibodies in otitisprone children demonstrates that they respond to the current pneumococcal conjugate vaccine (PCV)and are likely to respond to pneumolysin-based vaccines as effectively as healthy children.

Research

Clinical development strategy for a candidate group A streptococcal vaccine

This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin

Research

Vitamin D over the first decade and susceptibility to childhood allergy and asthma

We aimed to research relationships between 25(OH)D levels from birth to 10 y/o and susceptibility to allergic sensitization, respiratory issues and asthma.

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The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis.

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Influence of maternal obesity on the long-term health of offspring

Including immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health.

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Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian Children

Our results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children

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Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults

Type 2 inflammation is present in patients during virus-induced asthma exacerbations, to the same degree as non-viral exacerbations

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Distress and psychological morbidity do not reduce over time in carers of patients with high-grade glioma

his study aimed to determine how carer distress and psychological morbidity change over time following a patient's diagnosis of high-grade glioma