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Novel end points for clinical trials in young children with cystic fibrosisCystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.
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Dendritic cells and multiple sclerosis: Disease, tolerance and therapyMultiple sclerosis (MS) is a devastating neurological disease that predominantly affects young adults resulting in severe personal and economic impact.
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In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in miceAll alterations to lung mechanics following in utero arsenic exposure were recovered by adulthood.
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A phase 2 open-label safety and immunogenicity study of a meningococcal B bivalent rLP2086 vaccine in healthy adultsNo currently licensed and available vaccine has been shown to provide broad protection against endemic MnB disease.
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No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-caroteneThis intervention study found no increase in fracture risk among 2,322 adults who took a controlled, high-dose retinol supplement (25,000 IU retinyl...
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Familial aggregation of malignant mesothelioma in former workers and residents of Wittenoom, Western AustraliaClustering of cases of malignant mesothelioma within families has often been observed, but disentangling genetic and exposure effects has not been done.
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Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girlsEvidence that fructose intake may modify blood pressure is generally limited to adult populations.
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Genetic and epigenetic susceptibility to early life infectionTo date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological...
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The Childhood Leukemia International ConsortiumThe Childhood Leukemia International Consortium (CLIC) was established in 2007 to promote investigations of rarer exposures, gene-environment interactions...
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Effect of private insurance incentive policy reforms on trends in coronary revascularisation proceduresThere is currently a lack of evidence on the effect of the policy reforms on access to cardiovascular interventions in public and private hospitals in...