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Research

A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial

The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus bloodstream infection, a globally common and severe infectious disease, is treated. In a world first, the SNAP trial will simultaneously investigate the effects of multiple intervention modalities within multiple groups of participants with different forms of S. aureus bloodstream infection.

Research

Respiratory Syncytial Virus Reinfections in Children in Western Australia

Respiratory syncytial virus (RSV) reinfection in children is poorly understood. We examined the incidence, characteristics, and outcomes of hospital-attended RSV reinfections in children <16 years in Western Australia between 2012 and 2022.

Research

Antecedents of teenage pregnancy from a 14-year follow-up study using data linkage

This study identified possible antecedents of teenage pregnancy using linked data from administrative sources to create a 14-year follow-up from a cross-sect...

Aboriginal and Torres Strait Islander Suicide Prevention Evaluation Project (ATSISPEP)

The NATSISPEP will formally evaluate a range of existing Indigenous suicide prevention programs and services to develop an evidence base for 'what works'.

Aboriginal Research Standards

The Institute's Standards for the Conduct of Aboriginal Health Research outline our ways of working with Aboriginal communities and peoples.

Research

Linking a pharmaceutical claims database with a birth defects registry to investigate birth defect rates of suspected teratogens

Data linkage of population administrative data is being investigated as a tool for pharmacovigilance in pregnancy in Australia.

Research

Identification and genetic determination of an early life risk disposition for depressive disorder:

Progress in psychiatric genetics has been slow despite evidence of high heritability for most mental disorders

Research

Increased allergic immune response to Sarcoptes scabiei antigens in crusted versus ordinary scabies

Scabies, a parasitic skin infestation by the burrowing "itch" mite Sarcoptes scabiei, causes significant health problems for children and adults worldwide.