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For this study, we examined how Rett syndrome characteristics can be affected by X-inactivation for 2 of the common types of mutation - p.R168X and p.T158M.
We set out to describe the feeding difficulties and nutrition of girls with Rett syndrome and to examine what factors may be influencing their nutrition.
Therefore, we used video data to examine changes in hand function over time. We also investigated what other factors might influence these changes.
Research
BEACHES: Built Environments and Child Health in WalEs and AuStraliaThe BEACHES project aims to provide high quality evidence of aspects of the built environment which can be modified to reduce the negative impact on children’s physical activity, eating behaviours and weight status.
Research
Communication, fetal alcohol spectrum disorder and youth justiceInvestigators: Natalie Kippin This research aims to examine the communication abilities of young people sentenced to detention in Western Australia,
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Computational fluid-particle dynamic and pharmacokinetic assessment of electronic cigarette aerosols for improved understanding of their potential to impact healthThis project will use computational methods to assess the deposition of e-cigarette aerosols in the lungs, and the distribution of chemicals within e-cigarette aerosols throughout the body.
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Research
Defining target penicillin concentrations for subsequent studies of a reformulated long-acting benzathine penicillin prototypeAims: To determine the minimum inhibitory concentrations of penicillin G against a representative collection of Strep A strains; and to evaluate the impact of penicillin G concentration and size of bacterial inoculum on the prophylactic effect for Strep A strains
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Developing and characterising juvenile models of aggressive paediatric brain cancers for the evaluation of novel immunotherapiesNick Raelene Terrance Gottardo Endersby Johns MBChB FRACP PhD BSc (Hons) PhD Head of Paediatric and Adolescent Oncology and Haematology, Perth
Research
Developing new models of mitochondrial diseases using CRISPR/Cas technologiesAleksandra Filipovska BSc PhD Louis Landau Chair in Child Health Research; NHMRC Leadership Fellow; Deputy Director, ARC Centre of Excellence for