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Unravelling the mystery of persistent wheeze in children: Study reveals crucial immune cell differences

The study found the rare immune cells, known as plasmacytoid dendritic cells, showed clear signs of activation and virus defence in children with transient wheeze, whereas in children with persistent wheeze the same immune cells showed very limited activation without any signs of virus defence.

Early disease surveillance in young children with cystic fibrosis: A qualitative analysis of parent experiences

Early disease surveillance in young children with cystic fibrosis: A qualitative analysis of parent experiences Sensitive measures of early lung

Cystic Fibrosis Clinical Isolates of Aspergillus fumigatus Induce Similar Muco-inflammatory Responses in Primary Airway Epithelial Cells

Cystic Fibrosis Clinical Isolates of Aspergillus fumigatus Induce Similar Muco-inflammatory Responses in Primary Airway Epithelial Cells

Ivacaftor and Airway Inflammation in Preschool Children with Cystic Fibrosis

Ivacaftor and Airway Inflammation in Preschool Children with Cystic Fibrosis Authors: Paul McNally, Daryl Butler, Yuliya Karpievitch , Barry Linnane,

Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis

Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis

Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis Background: Serum Glycoprotein A (GlycA)

Early respiratory viral infections in infants with cystic fibrosis.

Early respiratory viral infections in infants with cystic fibrosis. Abstract Background: Viral infections contribute to morbidity in cystic fibrosis

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Rationale: No studies

Airway surface liquid pH is not acidic in children with cystic fibrosis

Airway surface liquid pH is not acidic in children with cystic fibrosis Modulation of airway surface liquid (ASL) pH has been proposed as a therapy

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics The study of