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Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsisThe aim of our study was to characterize the activity of TNAP on TLR agonists and assess the concentrations of plasma ALP during late-onset sepsis in newborns.
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Blueprint for the House Dust MiteThe completeness of the coverage of a genome assembly is a critical starting point for all genomic projects so considerable attention is given to the sequencing metrics, which showed high indicators of success.
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A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbationsTo introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation.
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Bacillus licheniformis in geogenic dust induces inflammation in respiratory epitheliumWe have previously demonstrated that mice exposed to geogenic dust PM10 experienced an exacerbation of inflammatory responses to influenza A virus.
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Early life innate immune signatures of persistent food allergyEarly life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood
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Macrolides in children with community-acquired pneumonia: Panacea or placebo?Pneumonia, most often caused by a respiratory virus, is common in childhood.
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A national guideline for the assessment and diagnosis of autism spectrum disorders in AustraliaThe Guideline aims to create greater consistency in diagnostic practices across the country to ensure individuals on the autism spectrum can receive the optimal care
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Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children.The present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric ARI.
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Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observedWe aim to provide our view of where we are and where we need to go as a community of clinicians and researchers who tackle the public health problem of asthma.
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Fetal alcohol spectrum disorder and youth justice: a prevalence study among young people sentenced to detention in Western AustraliaThis study of young people in detention in Western Australia, has documented a high prevalence of FASD and severe neurodevelopmental impairment