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PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding proteinOur findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis
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Midwives’ attitudes, beliefs and concerns about childhood vaccination: A review of the global literatureThe majority of midwives supported vaccination, although a spectrum of beliefs and concerns emerged
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Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidisOur findings suggest that prenatal exposure to inflammation may alter the risk of sepsis in preterm infants partly by modulation of monocyte responses to pathogens
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Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to-Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT)Urinary albumin-to-creatinine ratios at the higher end of the normal range at the age of 10-16 years is associated with an increased risk of progression to microalbuminuria
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ISPAD Clinical Practice Consensus Guidelines 2018: Assessment and management of hypoglycemia in children and adolescents with diabetesHypoglycemia is the commonest acute complication of type 1 diabetes
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Silver Russel syndrome in an aboriginal patient from AustraliaWe report a 4-year-old Australian Aboriginal girl who was born at 32 weeks gestation with features strongly suggestive of Silver-Russell syndrome
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Early developmental risk for subsequent childhood mental disorders in an Australian population cohortWe examined associations between developmental vulnerability profiles determined at the age of 5 years and subsequent childhood mental illness between ages 6 and 13 years in an Australian population cohort.
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Reducing harms related to alcohol use in pregnancy – policy and practice recommendationsThis issues brief outlines opportunities for change to support reduction of harms related to alcohol use in pregnancy
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The prevention, diagnosis and management of central venous line infections in childrenWith advancing paediatric healthcare, the use of central venous lines has become a fundamental part of management of neonates and children.
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Impetigo and scabies - Disease burden and modern treatment strategiesRecent data on the epidemiology of impetigo and scabies and describe the current evidence around approaches to individual and community based treatment