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Research
Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art ReviewReducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). However, a substantial number of individuals develop coronary atherosclerosis despite no SMuRFs. SMuRFless patients presenting with myocardial infarction have been observed to have an unexpected higher early mortality compared to their counterparts with at least 1 SMuRF.
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Fathers’ preconception smoking and offspring DNA methylationExperimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. We aim to identify epigenetic marks in offspring associated with father's preconception smoking.
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Incidence of Stroke in the Aboriginal and Non-Aboriginal Populations of Australia: A Data Linkage StudyMost estimates of stroke incidence among Aboriginal and Torres Strait Islander (hereinafter Aboriginal) Australians are confined to single regions and include small sample sizes. We aimed to measure and compare stroke incidence in Aboriginal and non-Aboriginal residents across central and western Australia.
The Kids Research Institute Australia is equipped with a diverse range of histology and microscopy equipment and analysis software to facilitate state-of-the-art imaging.
A Kimberley study seeking to better understand Strep A in remote settings is helping to guide new approaches to prevent acute rheumatic fever (ARF) – an auto-immune response that typically begins with a sore throat and causes high fever, tiredness and swollen joints.
In a world where TikTok dances and Minecraft adventures take centre stage, kids are spending more time online than ever before.
At just six months old, Tahlea Dalgety was flown from Geraldton to Perth with a slim chance of survival after contracting meningococcal disease.
Research
Impact of Host and Bacterial Metabolism on Antibiotic SusceptibilityAntimicrobial resistance (AMR) is a global healthcare emergency, directly causing 1.3 million deaths per year and predicted to increase dramatically over the coming decades. Understanding the molecular mechanisms underpinning antibiotic resistance is central to approaches for AMR surveillance and diagnosis in a clinical laboratory.
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Rehabilitation service provision and outcomes for children with stroke in Victoria and Western Australia in the pre-implementation era of clinical practice guidelinesThis study described the rehabilitation services accessed by children with stroke following acute admission to two Australian paediatric tertiary hospitals prior to the implementation of clinical practice guidelines. It also evaluated quality-of-care indicators for inpatient rehabilitation within these two settings.
Wiping out childhood ear infections could become a reality thanks to new research identifying the main bacteria responsible for recurrent ear infections and repeat ear surgeries.