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Research

The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1

Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1

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Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

Biological changes associated with T-ALL relapse and resistance are stochastic and highly individual

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Hospital admission for infection during early childhood influences developmental vulnerabilities at age 5 years

This study demonstrates a pervasive effect of early life infections that require hospital admission on multiple aspects of early child development

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Adolescent and young adult medicine in Australia and New Zealand: towards specialist accreditation

The RACP is advancing a three-tier strategy to build greater specialist capacity and sustain leadership in adolescent and young adult medicine

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Asymptomatic CMV infections in long-term renal transplant recipients are associated with the loss of FcRγ from LIR-1+ NK cells

CMV can be reactivated in symptom-free renal transplant recipients, affecting the phenotypic, and functional profiles of NK cells

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Lao PDR early childhood education project : snapshot three - child development

This snapshot highlights that children in Northern Lao PDR are developing poorly, with disparities in child development across different ethnic groups and family backgrounds

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Helicobacter pylori overcomes natural immunity in repeated infections

Helicobacter pylori infection does not promote an immune response protective against future reinfection

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Folate pathway gene polymorphisms and risk of childhood brain tumors: Results from an Australian case-control study

Recent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate...

Research

Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication

We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...

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Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-azar Dermal Leishmaniasis in Sudanese patients

Uniformly low expression of IFN and IFNGR1 in PKDL skin biopsies could explain parasite persistence