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Research

Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors

Acute lymphoblastic leukemia and childhood brain tumors are 2 of the most common forms of childhood cancer, but little is known of their etiology.

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T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide length

T-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus.

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ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.

Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable.

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Cancer and mental illness: Key issues in mental health

Over many years, it has been shown that cancer represents a significant proportion of excess mortality for people with mental illness.

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Evaluation in health promotion: Thoughts from inside a human research ethics committee

Health promotion research, quality improvement and evaluation are all activities that raise ethical issues.

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Re-evaluation of link between interpregnancy interval and adverse birth outcomes: Retrospective cohort study matching two intervals per mother

This study questions the causal effect of short interpregnancy intervals on adverse birth outcomes and points to the possibility of unmeasured or...

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Effectiveness of trivalent flu vaccine in healthy young children

This paper reports some of the findings from the Western Australian Influenza Vaccine Effectiveness Study, commenced in 2008, to evaluate a program providing...

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Examining ERBB2 as a candidate gene for susceptibility to leprosy (Hansen's disease) in Brazil

This study examines whether polymorphisms in the ERBB2 gene were associated with leprosy in primary and replication cohorts from northeastern Brazil.

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Effects of adopting the new global lung function initiative 2012 reference equations on the interpretation of spirometry

The aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012...

Research

Novel end points for clinical trials in young children with cystic fibrosis

Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.