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Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus. Aspiration of bile into the cystic fibrosis (CF) lung has
Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children
The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials
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The potential of antisense oligonucleotide therapies for inherited childhood lung diseases Antisense oligonucleotides (AOs) are an emerging
News & Events
Lung health of Aboriginal children hospitalised with chest infections improved following co-designed interventionA co-designed and culturally secure intervention to improve medical follow-up for Aboriginal children hospitalised with acute chest infections resulted in higher follow-up rates and improved longer-term lung health outcomes for children.
News & Events
Wal-yan Centre scholarship awardees to research interventions for improving lung healthAs part of the Wal-yan Respiratory Research Centre’s aim to support the next generation of scientists in children’s respiratory research, a competitive scholarship program was introduced this year.
News & Events
Discovery Centre lightens the load for hospital familiesThe opening of the Discovery Centre has made trips to Perth Children's Hospital much more enjoyable for mum Alianna Celisano and her three boys.
Research
Early childhood development strategy for the world's children with disabilitiesEarly childhood is foundational for optimal and inclusive lifelong learning, health and well-being. Young children with disabilities face substantial risks of sub-optimal early childhood development, requiring targeted support to ensure equitable access to lifelong learning opportunities, especially in low- and middle-income countries.
Research
Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trialCDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Ganaxolone, a neuroactive steroid, reduces the frequency of major motor seizures in children with CDD. This analysis explored the effect of ganaxolone on non-seizure outcomes.