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Early infancy is a critical period for immune development. In addition to being the primary food source during early infancy, human milk also provides multiple bioactive components that shape the infant gut microbiome and immune system and provides a constant source of exposure to maternal microbiota. Given the potential interplay between allergic diseases and the human microbiome, this study aimed to characterise the milk microbiome of allergic mothers.
ORIGINS has several sub-projects exploring allergy development within the cohort, with a focus on respiratory conditions such as asthma and nutritional strategies for allergy prevention.
ORIGINS sub-projects investigating the impact of the physical environment and lifestyle on health, development and chronic conditions.
IgE-mediated sensitisation to egg is common in infants. In some cases, the processes leading to egg sensitisation are established in early life, even before introduction to solid foods. The underlying mechanisms remain poorly understood.
Four The Kids Research Institute Australia-based biobanks which underpin a range of cancer, respiratory and early life research have received more than $450,000 in funding.
What if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?
At The Kids Research Institute Australia, we have a dedicated and diverse team of over 1,000 staff, students and honorary researchers.
Research data from more than one million Australian and Welsh children will be examined to help better understand how the built environment affects child health and obesity, as part of an international research project to be co-led by The Kids Research Institute Australia.
First-of-its-kind findings show that newborns exclusively fed colostrum in their first 72 hours of life were five times less likely to develop a peanut allergy by 12-18 months, and 11 times less likely to develop multiple food allergies (such as egg or cow’s milk) compared with infants who also received formula
ORIGINS, the largest longitudinal cohort study of its kind in Australia, delivered in partnership between The Kids Research Institute Australia and Joondalup Health Campus, has received $1.5 million funding from the Minderoo Foundation.