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Research

Improved Survival in Down Syndrome over the Last 60 Years and the Impact of Perinatal Factors in Recent Decades

Improved survival for children born with Down syndrome over the last 60 years has occurred incrementally, but disparities still exist

Research

Respiratory viruses in young South African children with acute lower respiratory infections and interactions with HIV

RV-A and RV-C are endemic in South African children and HIV infection may be protective against RSV and bronchiolitis.

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Gross motor performance in children prenatally exposed to alcohol and living in remote Australia

A higher than expected proportion of children with fetal alcohol spectrum disorders had gross motor scores that indicated impairment and need for therapy

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Lipidomics reveals associations of phospholipids with obesity and insulin resistance in young adults

Lipidomic biomarkers associated with obesity and IR using plasma samples from a population-based cohort of young adults

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Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

Our data demonstrate a causal relationship between activating Pik3ca mutations and the genesis of venous malformations

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Change in residential remoteness during the first 5 years of life in an Australian cerebral palsy cohort

To determine if families of children with cerebral palsy living in Australia move to less remote areas between birth and 5 years.

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Spinal fusion in girls with Rett syndrome: Post-operative recovery and family experiences

Rett syndrome is a severe neurodevelopmental disorder mainly affecting females and scoliosis is a common co-morbidity. Spinal fusion may be recommended if...

Research

The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung function

In this study, we aimed to uncover the molecular mechanisms contributing to altered lung structure and function.

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Prevention and Natural History of Food Allergy

The rise in food allergy is more rapid than genetic deviation would allow and the current consensus is that environmental factors integrally linked to the...

Research

A randomized phase I study of the safety and immunogenicity

In this study of healthy adults aged 50-85 and 18-24 years, SA3Ag elicited a rapid and robust immune response and was well tolerated, with no notable safety...