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An Observational Study to Assess the Effectiveness of 4CMenB against Meningococcal Disease and Carriage and Gonorrhea in Adolescents in the Northern Territory, Australia—Study ProtocolInvasive meningococcal disease (IMD) causes significant morbidity and mortality worldwide with serogroup B being the predominant serogroup in Australia and other countries for the past few decades. The licensed 4CMenB vaccine is effective in preventing meningococcal B disease. Emerging evidence suggests that although 4CMenB impact on carriage is limited, it may be effective against gonorrhoea due to genetic similarities between Neisseria meningitidis and Neisseria gonorrhoeae.
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Statistical analysis plan for the OPTIMUM study: optimising immunisation using mixed schedules, an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine scheduleThe purpose of this double-blind, randomised, controlled trial is to compare allergic outcomes in children following vaccination with acellular pertussis (aP) antigen (standard of care in Australia) given at 2 months of age versus whole cell pertussis (wP) in the infant vaccine schedule.
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General practitioners’ perceptions of their communication with Australian Aboriginal patients with acquired neurogenic communication disordersGPs report difficulty recognising acquired communication disorders and their lack of prioritising assessment and treatment of communication ability after brain injur
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Early-life exposure to electronic cigarettes: cause for concernThere are a multitude of ways that, with respect to early-life exposures and health, electronic nicotine delivery systems are a cause for concern
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A Qualitative Exploration of Electronic Image Sharing Among Young People: Navigating the Issues of Conformity, Trust, Intention, and ReputationThis research sought to explore the main factors affecting young people's image-sharing behaviors, particularly in the context of peer relationships and norms
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Qualitative study of psychosocial factors impacting on Aboriginal women's management of chronic diseaseThe caring roles and responsibilities Aboriginal women have in their community impact on their health
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Harmonised collection of data in youth mental health: Towards large datasetsThe use of this core set of data will facilitate the pooling of psychopathological and neurobiological data into large datasets
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Increased facial asymmetry in autism spectrum conditions is associated with symptom presentationSignificantly greater depth-wise facial asymmetry was identified in autistic children relative to the two comparison groups
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Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiologyHere, we identifyied 12 suggestively significant loci associated with intake of any macronutrient in 91,114 European ancestry participants
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Immune-mediated ECM depletion improves tumour perfusion and payload deliveryWe have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds