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A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apneaWe hypothesized that a dual-channel portable monitor (PM) device could accurately identify patients who have a high pretest probability of obstructive sleep...
Research
Increasing accurate self-report in surveys of pregnancy alcohol useReporting bias may contribute to ambiguous and conflicting findings on fetal effects of low to moderate pregnancy alcohol exposure.
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Lessons from 50 years of curing childhood leukaemiaOne of the great success stories of modern medicine is undoubtedly the remarkable improvement in outcome for childhood cancer, achieved through the work of...
Research
How low can we go? Recognizing infants at high risk of cerebral palsy earlierThis paper is a timely reminder that we must recognise infants at high risk of cerebral palsy earlier using evidence-based assessments.
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Prenatal factors in singletons with cerebral palsy born at or near termThis article discusses the prenatal factors in singletons with cerebral palsy born at or near term.
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Gastrointestinal dysmotility in rett syndromeThrough evidence review and the consensus of an expert panel, we developed recommendations for the clinical management of gastroesophageal reflux disease,...
Research
Defective respiratory tract immune surveillance in asthma : A primary causal factor in disease onset and progressionThe relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate.
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Rhinovirus exacerbates house-dust-mite induced lung disease in adult miceIn this study, we combined human-rhinovirus infection with a clinically relevant mouse model of aero-allergen exposure using house-dust-mite in an attempt to...
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Comparative drug screening in NUT midline carcinomaThe NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed.
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Multinodular goiter in children: An important pointer to a germline DICER1 mutationThis paper is a clinical report of a boy presenting with a kidney cyst. Family history and genetic analysis revealed the family had a mutation in the DICER1...