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News & Events
Education “word gap” emerges at 18 months of age in Australian familiesUniversity-educated parents in Australia speak more words to their children on average than parents with only a high-school education, with the gap emerging at around 18 months of age.
News & Events
Back to school: How to pack a healthy lunchbox to keep your child fuelled up for learning and playPlenty of parents will tell you the daily lunchbox dilemma is one thing they did not miss during the summer holidays.
News & Events
New national role for The Kids’ Executive DirectorThe Australian Government has appointed the National Health and Medical Research Council (NHMRC) Council for 2024 to 2027.
News & Events
COVID-19 in WA: Why having our kids wear masks at school is the correct callWest Australian children as young as Year 3 are now turning up to school in masks, presenting a new challenge for kids, parents and schools.
News & Events
New centre to focus on breaking the cycle of disadvantageThe ARC Centre of Excellence will conduct world-leading research to investigate new ways of tackling entrenched social and economic disadvantage.
Research
The interplay between sarcoma and surgery-induced wound healingIn this project, we are using systems biology approaches to map the wound healing response in sarcoma following surgery to identify new treatments that can prevent sarcoma relapse.
Research
Deletions in the CDKL5 5 untranslated region lead to CDKL5 deficiency disorderPathogenic variants in the cyclin-dependent kinase-like 5 (CDKL5) gene are associated with CDKL5 deficiency disorder (CDD), a severe X-linked developmental and epileptic encephalopathy.
Research
Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive CombinationsAntibodies that target immune checkpoints such as cytotoxic T lymphocyte antigen 4 (CTLA‐4) and the programmed cell death protein 1/ligand 1 (PD-1/PD-L1) are now a treatment option for multiple cancer types. However, as a monotherapy, objective responses only occur in a minority of patients. Chemotherapy is widely used in combination with immune checkpoint blockade (ICB). Although a variety of isolated immunostimulatory effects have been reported for several classes of chemotherapeutics, it is unclear which chemotherapeutics provide the most benefit when combined with ICB.
Research
Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of actionChemotherapy has historically been the mainstay of cancer treatment, but our understanding of what drives a successful therapeutic response remains limited.
Research
The ecological determinants of severe dengue: A Bayesian inferential modelLow socioeconomic status (SES), high temperature, and increasing rainfall patterns are associated with increased dengue case counts. However, the effect of climatic variables on individual dengue virus (DENV) serotypes and the extent to which serotype count affects the rate of severe dengue in Mexico have not been studied before.