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Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansionWe found transient pDC depletion during Pneumovirus infection alone predisposed to severe bronchiolitis in early life and subsequent asthma after reinfection.
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High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitisHigh dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis
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Larger Than Life: Injecting Hope into the Planetary Health ParadigmWe argue that the success of planetary health solutions is predicated on a more sophisticated understanding of the psychology of prevention and intervention at all scales
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Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologiesInnate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease.
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Exploring factors impacting early childhood health among Aboriginal and Torres Strait Islander families and communitiesThe impact of perinatal outcomes, maternal social and health outcomes and level of culturally secure service availability on the health outcomes of Western Australian Aboriginal infants and children
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Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case seriesThe promotion of a low carbohydrate diet in media is in contrast to published pediatric diabetes guidelines that endorse a balanced diet from a variety of foods
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Cohort profile: Pregnancy and childhood epigenetics (PACE) consortiumCurrently, DNA methylation is the most studied epigenetic phenomenon in large populations
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Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd EditionThe realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence.
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Australian Aboriginal children with otitis media have reduced antibody titers to specific nontypeable Haemophilus influenzae vaccine antigensdecreased serum IgG responses to NTHi outer membrane proteins may contribute to the development of chronic and severe OM in Australian Aboriginal children
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Autonomic breathing abnormalities in Rett syndrome: caregiver perspectives in an international database studyOur aims were to characterize the abnormal breathing patterns and abdominal bloating, investigate the distribution of these by age and mutation type and examine their impact and management from a caregiver perspective.