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Research

A comparative study of extracellular vesicle-associated and cell-free DNA and RNA for HPV detection in oropharyngeal squamous cell carcinoma

Our study demonstrates that although HPV-DNA/RNA can be detected in EV associated DNA/RNA, cf-DNA/RNA is the more sensitive liquid biopsy medium

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Development of a referral pathway framework for foetal alcohol spectrum disorder in the Pilbara

The process of referral pathway development provided a service mapping and gapping exercise to facilitate service integration

Research

Effects of serotonin depletion and dopamine depletion on bimodal divided attention

The results indicate a possible dissociation between the effects of a diminished brain 5-HT and DA synthesis on the performance in a bimodal divided attention task

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Impact of heart disease on maternal, fetal and neonatal outcomes in a low-resource setting

Occult maternal heart disease may be responsible for a substantial proportion of adverse pregnancy outcomes in low-resource settings

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Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma

We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII

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Temporal trends and socioeconomic differences in acute respiratory infection hospitalisations in children: an intercountry comparison of birth cohort studies

Admissions for ARI were higher in Western Australia and displayed greater socioeconomic disparities than England and Scotland, where ARI rates are increasing

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Single-breath washout and association with structural lung disease in children with cystic fibrosis

Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT

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Developmental vitamin D deficiency produces behavioral phenotypes of relevance to Autism in an animal model

Here we investigate these features in an animal model related to autism spectrum disorder - the DVD-deficient rat

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Exercise Management for Young People With Type 1 Diabetes: A Structured Approach to the Exercise Consultation

This review provides a structured approach to assist in formulating person-specific exercise management plans for young people with T1D

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Survival and mortality in cerebral palsy: Observations to the sixth decade from a data linkage study of a total population register and National Death Index

Since 1990 mortality for those with severe cerebral palsy in Western Australia has tended to shift from childhood to early adulthood