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Research

Validation of an Asbestos Job-Exposure Matrix (AsbJEM) in Australia: Exposure-Response Relationships for Malignant Mesothelioma

Accuracy of the AsbJEM in determining exposure-response relationships between asbestos exposure estimates and malignant mesothelioma incidence

Research

An update on allergy and anaphylaxis in pediatric anesthesia

We review the pathophysiology of hypersensitivity reactions and the implications for anesthesia of food allergy, atopy, and family history of allergy in children

Research

Optimisation of multiplex immunofluorescence for a non-spectral fluorescence scanning system

Here we present two 5-colour immunofluorescence panels designed for T cell characterisation in human colorectal tissue

Research

New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment

We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL

Research

Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 years

We provide new evidence to support current guidelines for orchidopexy before age 18 months to decrease the risk of future testicular cancer and infertility

Research

ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing

Assessment of airway hyperresponsiveness are valuable tools to understand and to monitor airway function and to characterise the underlying asthma phenotype to guide therapy

Research

Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis

Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target

Research

A novel, palatable paediatric oral formulation of midazolam: Pharmacokinetics, tolerability, efficacy and safety

We conclude that the novel chocolate-based formulation of midazolam provides improved tolerability while remaining efficacious

Research

Research priority setting in childhood chronic disease: a systematic review

Research priority setting activities in paediatric chronic disease cover many discipline areas and have elicited a broad range of topics

Research

Socioeconomic status and early child development in East Asia and the Pacific: The protective role of parental engagement in learning activities

Results indicated the existence of SES gradients in early development in multiple domains in China, Mongolia, Papua New Guinea, Timor-Leste, and Vanuatu