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Research

Genetic and epigenetic susceptibility to early life infection

To date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological...

Research

A phase 2 open-label safety and immunogenicity study of a meningococcal B bivalent rLP2086 vaccine in healthy adults

No currently licensed and available vaccine has been shown to provide broad protection against endemic MnB disease.

Research

The Childhood Leukemia International Consortium

The Childhood Leukemia International Consortium (CLIC) was established in 2007 to promote investigations of rarer exposures, gene-environment interactions...

Research

No dose-dependent increase in fracture risk after long-term exposure to high doses of retinol or beta-carotene

This intervention study found no increase in fracture risk among 2,322 adults who took a controlled, high-dose retinol supplement (25,000 IU retinyl...

Research

Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls

Evidence that fructose intake may modify blood pressure is generally limited to adult populations.

Research

Re-evaluation of link between interpregnancy interval and adverse birth outcomes: Retrospective cohort study matching two intervals per mother

This study questions the causal effect of short interpregnancy intervals on adverse birth outcomes and points to the possibility of unmeasured or...

Research

Maternal alcohol consumption during pregnancy and the risk of orofacial clefts in Infants: A Systematic Review and Meta-Analysis

This paper evaluated the association between maternal consumption of alcohol during pregnancy and the occurrence of cleft lip and palates in infants by...

Research

A study of handling cytotoxic drugs and risk of birth defects in offspring of female veterinarians

This paper examined the association of occupational exposure to handling cytotoxic drugs at work with risk of birth defects among a cohort of female...

Research

Vitamin D status and ill health

This paper is a comment in response to a review of Vitamin D status and its association with ill health.

Research

Maladaptive parenting and child emotional symptoms in the early school years

The current study investigated whether being exposed to maladaptive parenting (high hostility and low warmth) and/or marital conflict in infancy is...