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Research

Expanding the clinical picture of the MECP2 Duplication syndrome

People with two or more copies of MECP2 gene, located at Xq28, share clinical features and a distinct facial phenotype called MECP2 Duplication syndrome.

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Identification of genes differentially regulated by vitamin D deficiency that alter lung pathophysiology and inflammation in allergic airways disease

Vitamin D deficiency exacerbates house dust mite-induced inflammation and alterations in lung structure and function

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Influence of the day care, home and neighbourhood environment on young children's physical activity and health: protocol for the PLAYCE observational study

The PLAYCE study will empirically investigate the relative and cumulative influence of the day care, and home environment on preschoolers’ physical activity

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Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner

Maintaining sufficient vitamin D is necessary for optimal lung health, and vitamin D may modulate the lung microbiome in a sex-specific fashion

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Sun exposure and its effects on human health: Mechanisms through which sun exposure could reduce the risk of developing obesity and cardiometabolic dysfunction

The cardiometabolic protective effects of ultraviolet radiation and mechanistic pathways through which ultraviolet radiation could be beneficial.

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Asbestos-Related Non-Malignant Pleural Disease and Mesothelioma

This chapter deals with asbestos-related non-malignant pleural disease and mesothelioma.

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The evolution of clinical trials for infant acute lymphoblastic leukemia

Despite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has...

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Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3

Otitis media (OM) is a common childhood disease characterised by middle ear effusion and inflammation.

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Extensive Diversity of Streptococcus pyogenes in a Remote Human Population Reflects Global-Scale Transmission Rather than Localised Diversification

The Indigenous population of the Northern Territory of Australia (NT) suffers from a very high burden of Streptococcus pyogenes disease, including cardiac...

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Energy drink consumption among young Australian adults: Associations with alcohol and illicit drug use

Australian energy drink users tend to have heavier alcohol consumption patterns be a cigarette smoker and use illicit drugs relative to non-users.