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Madi Age 19. Volunteer Coordinator, Discovery Centre volunteer. In a world that is constantly evolving and adapting, research is crucial
Chloe Mum of two, Tom and Alexis. Community fundraiser. When our eldest child Tom was first diagnosed, I really didn’t know much about
News & Events
Meet the Finalists: Illuminate PitchFest 2025We are excited to introduce ten trailblazing researchers who will be taking to the stage this February to pitch their bold and innovative ideas to our philanthropic community.
News & Events
Funding boost for childhood cancer research projectsProjects to improve outcomes for leukaemia patients and reduce skin cancer rates in young Aboriginal people have received funding through Cancer Council WA.
News & Events
Tuberculosis expert named a Rising Star finalistA leading tuberculosis researcher from The Kids Research Institute Australia and Curtin University has been named a finalist for the Association of Australian Medical Research Institutes (AAMRI) 2024 Rising Star Award.
News & Events
New Chair for The Kids Research Institute AustraliaBusiness leader Naomi Flutter has been appointed Chair of The Kids Research Institute Australia.
News & Events
The Kids Research Institute Australia's Mitch Messer wins at WA of the Year AwardsThe Kids Research Institute Australia extends its warmest congratulations to health consumer champion Mitch Messer, who won the Community category at the 2024 West Australian of the Year awards last night.
News & Events
The Kids on the road to Broome again in 2024 thanks to Federal Government grantThe Kids Research Institute Australia will bring science to the Kimberley for a second year in 2024 after the Federal Government today announced a $20,000 grant for the Institute to deliver the Broome STEM Festival.
Research
Literacy and Numeracy Underachievement in Boys and Girls With ADHDChildren with ADHD are disadvantaged from an early age in key areas of learning, and this risk increased with reduction in gestational age at birth
Research
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastomaMedulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.