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Research

Vitamin D deficiency causes airway hyperresponsiveness and increases airway smooth muscle mass in the lungs of female BALB/c mice

We tested whether there is a causal association between vitamin D deficiency, airway smooth muscle (ASM) mass, and the development of airway hyperresponsiveness

Research

Common variation contributes to the genetic architecture of social communication traits

Social communication difficulties represent an autistic trait that is highly heritable and persistent during the course of development.

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“I have a good life”: the meaning of well-being from the perspective of young adults with Down syndrome

The purposes of this study were to explore what makes for a "good life" from the perspective of young adults with Down syndrome and to identify the barriers...

Research

The Differential Influence of Contextual Risks on Psychosocial Functioning and Participation of Australian Aboriginal Youth

Methodological issues and implications for interventions to support young Aboriginal people's adaptation are discussed.

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Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

The outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%.

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Recommendations from a consensus development workshop on the diagnosis of fetal alcohol spectrum disorders in Australia.

Fetal alcohol spectrum disorders (FASD) are underdiagnosed in Australia, and health professionals have endorsed the need for national guidelines for diagnosis.

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Chest computed tomography: a validated surrogate endpoint of cystic fibrosis lung disease?

Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions.

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Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea

Our objectives were to describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA) and to investigate MVC risk...

Research

A preliminary study of fetal head circumference growth in Autism Spectrum Disorder

Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD).

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Unraveling the genetics of otitis media: From mouse to human and back again

Otitis media (OM) is among the most common illnesses of early childhood, characterised by the presence of inflammation in the middle ear cavity...