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Reports and Findings

Research

P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages

The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacte

Research

Valproate and risk of fracture in Rett syndrome

This study investigated the relationships between fracture risk and commonly used AEDs in Rett syndrome.

Research

Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA

The DNA lesion 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a urinary marker of oxidative stress, is produced from reactions of reactive oxygen

Research

Anxiety disorders and cigarette smoking: Results from the Australian Survey of Mental Health and Wellbeing

The aim of this study was to describe current and daily smoking rates, and smoking cessation rates in adults with anxiety disorders

Research

Start Stronger, Live Longer National Aboriginal Health Worker Symposium: Final Report

The Rio Tinto Aboriginal Health Partnership marries Rio Tinto's commitment and dedication to community investment with research expertise of the Telethon Inst

Research

UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Research

Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models

The incidence of atopic disease has increased dramatically during recent decades and the potential immunoregulatory influence of the microbiota in these...

Research

Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Research

Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbations

Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.

Research

Type 1 diabetes in children - emergency management

Fifteen to sixty-seven percent of patients with new onset type 1 diabetes mellitus (T1DM) present in diabetic ketoacidosis (DKA), of which approximately...