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Nutrition in Early Life

The vision of the Nutrition in Early Life team is to work together with the community to produce quality research, for improving our knowledge of how a mother’s diet during pregnancy and breastfeeding can improve both her and her child’s health.

The Nutrition in Early Life team conducts research investigating nutritional strategies for improved maternal and child health, including clinical trials, mechanistic studies and translatable research activities.

Our research includes identifying nutritional and environmental factors which influence the developing human immune system, particularly factors which predispose to allergic diseases (eczema, food allergy, hay fever and asthma in early childhood), as well as intervention studies for the prevention of allergic disease in childhood.

Team Highlights

  1. We have recruited more than 2000 mothers and babies in a current NHMRC funded large-scale multi-centre (Adelaide, Perth, Melbourne and Sydney) food allergy prevention study – known as the PrEggNut Study. This study is aiming to determine whether the risk of developing a food allergy can be reduced by a maternal diet rich in eggs and peanuts during pregnancy and breastfeeding.
  2. In 2023, we have completed the 1-year-old child follow-up and commenced the 5-year-old child follow-up of the NHMRC funded allergy prevention study, which recruited 652 mothers and their babies – known as the SYMBA Study. This study is aiming to determine whether the risk of a child developing any allergic diseases (including eczema, food allergy, asthma and hay fever) can be reduced by a maternal diet supplemented with prebiotics (a type of fibre) during pregnancy and breastfeeding.
  3. We have commenced recruitment for a new NHMRC funded large-scale multi-centre (Perth and Melbourne) food allergy prevention study – known as the Nuts For Babies Study. This study is aiming to determine whether the amount of nuts a mother eats during breastfeeding can reduce the risk of nut allergy development in babies.

Team leader

Debbie Palmer
Debbie Palmer

BSc BND PhD

Head, Early Life & Life-Course Health Program; Team Lead, Nutrition in Early Life

Team members (6)

Anita Jorgensen

Anita Jorgensen

National PrEggNut Study Coordinator

Emma Prescott

Emma Prescott

SYMBA Study Coordinator

Summer Walker

Summer Walker

Research Assistant

Deborah Lawrence

Deborah Lawrence

Research Nurse

Michelle Thompson

Michelle Thompson

Research Assistant

Kelly Faulkner

Kelly Faulkner

Research Nurse

Nutrition in Early Life projects

Featured projects

The PrEggNut Study – Maternal diet rich in eggs and peanuts to reduce food allergies: a randomised controlled trial

The SYMBA Study - Promoting Gut Health (SYMBiosis) for Allergy prevention

Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study

Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM. 

Role of antenatal maternal diet

Nutrition is a modifiable lifestyle factor that may play a role in allergic disease prevention. This article summarizes current evidence on the antenatal diet as a consideration for strategies to prevent child food allergy. As eczema in early infancy substantially increases the risk of food allergy development, the effects of maternal dietary intakes during pregnancy on infant eczema outcomes will also be discussed.

Maternal Allergic Disease Phenotype and Infant Birth Season Influence the Human Milk Microbiome

Early infancy is a critical period for immune development. In addition to being the primary food source during early infancy, human milk also provides multiple bioactive components that shape the infant gut microbiome and immune system and provides a constant source of exposure to maternal microbiota. Given the potential interplay between allergic diseases and the human microbiome, this study aimed to characterise the milk microbiome of allergic mothers.

Cohort Profile: The ORIGINS pregnancy and birth cohort

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