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Research

Safety and Immunogenicity of MF59-Adjuvanted Cell Culture-Derived A/H5N1 Subunit Influenza Virus Vaccine: Dose-Finding Clinical Trials in Adults and the Elderly

In adult and elderly participants, the full-dose aH5N1c vaccine formulation was well tolerated and met US and European licensure criteria for pandemic vaccines

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Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study

Findings provide novel insight into the composition of the gut virome during pregnancy and demonstrate a distinct profile of viruses in women with type 1 diabetes

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Mothers’ understanding of infant feeding guidelines and their associated practices: A qualitative analysis

The findings indicated that in spite of continued promotion of the AIFG over the past ten years achieving the around six months guideline is challenging

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Cerebral palsy trends in Australia (1995-2009): a population-based observational study

Birth prevalence of CP declined. Encouragingly, the percentage of children with CP whose disability was moderate to severe also decreased

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Serotonergic contributions to human brain aggression networks

We investigated the influence of brain serotonin modulation and MAOA genotype on functional amygdala connectivity during aggressive behavior

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Multiomics and Systems Biology Are Needed to Unravel the Complex Origins of Chronic Disease

In this concept paper, we discuss multiomic approaches to studying immune dysregulation and highlight some of the challenges and opportunities

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The prevalence of mental health disorders and symptoms in children and adolescents with cerebral palsy: a systematic review and meta-analysis

Mental health conditions and problems are often reported in children and adolescents with CP. A systematic review was undertaken to describe their prevalence.

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Patterns of sedentary time and ambulatory physical activity in a Danish population of girls and women with Rett syndrome

We aimed to: (1) describe the patterns of sedentary time and daily steps and (2) identify the association of individual and environmental characteristitics.

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Linking FANTOM5 CAGE peaks to annotations with CAGEscan

Here, we present the production and quality control of CAGEscan libraries from 56 FANTOM5 RNA sources

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Broad perspectives of allergen specific immunotherapy

Allergen specific immunotherapy aims to subvert or divert immune responses to allergens to ones that do not cause immunological hypersensitivities.