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Research

Sensitive measures of early lung disease are being integrated into therapeutic trials and clinical practice in cystic fibrosis (CF). The impact of early disease surveillance (EDS) using these novel and often intensive techniques on young children and their families is not well researched.

Research

Cholangiocarcinoma (CCA) is a serious health challenge with low survival prognosis. The liver fluke, Opisthorchis viverrini, plays a role in the aetiology of CCA, through hepatobiliary abnormalities: liver mass (LM), bile duct dilation, and periductal fibrosis (PDF). A population-based CCA screening program, the Cholangiocarcinoma Screening and Care Program, operates in Northeast Thailand. Hepatobiliary abnormalities were identified through ultrasonography.

Research

In recent years the study of the commensal microbiota is driving a remarkable paradigm shift in our understanding of human physiology. However, intrinsic technical difficulties associated with investigating the Microbiomics of some body niches are hampering the development of new knowledge. This is particularly the case when investigating the functional role played by the human microbiota in modulating the physiology of key organ systems. A major hurdle in investigating specific Microbiome communities is linked to low bacterial density and susceptibility to bias caused by environmental contamination.

Research

ClC-7 is a chloride-proton antiporter of the CLC protein family. In complex with its accessory protein Ostm-1, ClC-7 localizes to lysosomes and to the osteoclasts' ruffled border, where it plays a critical role in acidifying the resorption lacuna during bone resorption. Gene inactivation in mice causes severe osteopetrosis, neurodegeneration, and lysosomal storage disease. Mutations in the human CLCN7 gene are associated with diverse forms of osteopetrosis.

The Kids Research Institute Australia's annual report highlights the accomplishments of our researchers, furthering our mission to secure a happier, healthier future for kids everywhere.

The Kids Research Institute Australia's annual report highlights the accomplishments of our researchers, furthering our mission to secure a happier, healthier future for kids everywhere.

At The Kids Research Institute Australia, our vision is simple - happy healthy kids. We bring together community, researchers, practitioners, policy makers and funders who share our mission to improve the health, development and lives of children and young people through excellence in research.

At The Kids Research Institute Australia, our vision is simple - happy healthy kids. We bring together community, researchers, practitioners, policy makers and funders who share our mission to improve the health, development and lives of children and young people through excellence in research.

At The Kids Research Institute Australia, our vision is simple - happy healthy kids. We bring together community, researchers, practitioners, policy makers and funders who share our mission to improve the health, development and lives of children and young people through excellence in research.

We rely on our fundraisers enormously. Not only are they out there raising money to help fund our research into children’s health, they’re raising awareness within the community about the broad scope of work we do. They are helping to create hope for children and their families. Want to get involved?