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Research

School-based intervention to address self-regulation and executive functioning in children attending primary schools in remote Australian Aboriginal communities

Executive functioning and self-regulation influence a range of outcomes across the life course including physical and mental health, educational success, and employment

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Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

The mutant Der p 2 had altered structure and reduced ability to stimulate pro-inflammatory responses and to bind IgE

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Investing in school readiness: A comparison of different early childhood education pathways in rural Indonesia

This paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways

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House Dust Mite Allergens: New Discoveries and Relevance to the Allergic Patient

Recent findings on house dust allergens and their contribution to knowledge that will significantly impact current and future allergy treatments are appraised

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Implementing and Evaluating Interventions to Improve School Readiness and Early Literacy

The implementation of the Pacific early age readiness and learning program has generated significant data, evidence, operational experience, and knowledge

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Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia

Chinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression

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A population health approach in education to support children's early development: A Critical Interpretive Synthesis

The results from this review indicate that it would indeed be plausible to adapt the population health approach to sites and schools

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Chronic cat allergen exposure induces a Th2 cell-dependent IgG4 response related to low sensitization

This study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.

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Latent profiles of early developmental vulnerabilities in a New South Wales child population at age 5 years

Patterns of early childhood developmental vulnerabilities may provide useful indicators for particular mental disorder outcomes in later life

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Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children

We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.

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Relationship between the neighbourhood built environment and early child development

The relationship between features of the neighbourhood built environment and early child development was investigated

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Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastoris

The house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.

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The 2015 Middle Childhood Survey (MCS) of mental health and well-being at age 11 years in an Australian population cohort

most children report mental health and well-being, but the population distribution spanned the full range of possible scores on every construct.

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House dust mite allergens in asthma and allergy

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against

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Investigations into the role of ST2 in acute asthma in children

This study investigated the potential role of ST2 in children with acute asthma.

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Clinical Management of Staphylococcus aureus Bacteremia in Neonates, Children, and Adolescents

Staphylococcus aureus is a common cause of community and health care-associated bacteremia, with authors of recent studies estimating the incidence of S aureus bacteremia (SAB) in high-income countries between 8 and 26 per 100 000 children per year. Despite this, <300 children worldwide have ever been randomly assigned into clinical trials to assess the efficacy of treatment of SAB.

Research

Quality of benzathine penicillin G: A multinational cross-sectional study

Benzathine penicillin G (BPG) is used as first-line treatment for most forms of syphilis and as secondary prophylaxis against rheumatic heart disease (RHD). Perceptions that poor quality of BPG is linked to reported adverse effects and therapeutic failure may impact syphilis and RHD control programs. Clinical networks and web-based advertising were used to obtain vials of BPG from a wide range of countries.