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Early nutrition and its effect on allergy development

Nutrition is one of the most easily modifiable environmental factors during early life that may play a role in allergic disease prevention.

Blueprint for the House Dust Mite

The completeness of the coverage of a genome assembly is a critical starting point for all genomic projects so considerable attention is given to the sequencing metrics, which showed high indicators of success.

The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1

Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1

Barriers and Considerations for Diagnosing Rare Diseases in Indigenous Populations

Advances in omics and specifically genomic technologies are increasingly transforming rare disease diagnosis. However, the benefits of these advances are disproportionately experienced within and between populations, with Indigenous populations frequently experiencing diagnostic and therapeutic inequities. The International Rare Disease Research Consortium (IRDiRC) multi-stakeholder partnership has been advancing toward the vision of all people living with a rare disease receiving an accurate diagnosis, care, and available therapy within 1 year of coming to medical attention. In order to further progress toward this vision, IRDiRC has created a taskforce to explore the access barriers to diagnosis of rare genetic diseases faced by Indigenous peoples, with a view of developing recommendations to overcome them.

Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia

Chinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression

Children with chronic suppurative lung disease have a reduced capacity to synthesize interferon-gamma in vitro in response to non-typeable Haemophilus influenzae

The aim of this study was to identify features of innate, cell-mediated and humoral immunity that may increase susceptibility to respiratory infections in...

A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei

Scabies infestations are difficult to diagnose clinically and current serologic tests have less than 50% accuracy...

Species-Specific and Cross-Reactive IgG1 Antibody Binding to Viral Capsid Protein 1 (VP1) Antigens of Human Rhinovirus Species A, B and C

Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children...