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Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation (CRICKET)—study protocol for an international multicentre prospective observational study

Critical Events in Anaesthetised Kids undergoing Tracheal Intubation (CRICKET) is a prospective, international multicentre observational study with the objective of capturing, assessing, and analysing critical events associated with tracheal intubation in children.

Psychological wellbeing outcomes across genders in childhood and adolescence aged 8–18 years: a population-level perspective

This study aimed to examine the difference in levels of psychological wellbeing outcomes of binary and non-binary transgender and cisgender students aged 8–18 years in South Australia using population-level data.

The impact of a dog-facilitated mobile physical activity intervention on children’s social–emotional development: a randomized controlled trial

Dog ownership has been suggested to be positively associated with children's physical, social, and emotional development. This study investigated the effect of a mobile health dog-facilitated physical activity intervention on young children's social-emotional development and attachment to the family dog.

The longitudinal network of social and emotional development in middle childhood

The understanding of children's social and emotional development in middle childhood is critical to promote well-being throughout the life course. Children who fail to develop social and emotional competencies are more likely to experience difficulties in adulthood and, in the worst case, psychopathology. The current study will employ Cross-Lagged Network Models to investigate children's social and emotional development among Australian children aged 6 to 10 years. 

Tracking Plasmodium knowlesi through faecal DNA for monitoring zoonotic transmission in wild macaques across Southeast and South Asia

We conducted the non-invasive surveillance of Plasmodium knowlesi in wild macaques using 4,752 faecal samples collected across nine endemic countries. 

Enhancing a diverse population: the American Thoracic Society Mentoring Program for Underrepresented in Medicine

Citation: Wang KCW, Lawrence K, Wisnivesky JP, Diaz AA. Enhancing a diverse population: the American Thoracic Society Mentoring Program for

Abdominal Imaging at Initial Diagnosis and Following Relapse in Children With Acute Lymphoblastic Leukaemia

Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. It is characterised by the proliferation of immature lymphoid cells capable of infiltrating bone marrow, blood and extramedullary sites. Five-year overall survival rates exceed 90% with current multidrug chemotherapeutic regimens. This manuscript reviews the abdominal imaging features of leukaemic infiltration in children with ALL at the time of initial diagnosis and following relapse.

Improving Outcome Reporting in Paediatric Airway Management in Clinical Trials (IMPACT): A Study Protocol for Core Outcomes and Clinical Endpoints

Although clinical trials are fundamental to advancing evidence-based practice, significant heterogeneity in outcome reporting poses a considerable challenge to the validity of systematic reviews. This inconsistency impedes the ability to compare, synthesise and interpret research findings effectively. In the field of paediatric airway management, this issue is particularly relevant because of the low incidence of critical events and the related high morbidity and mortality. The issue of inadequate and variable outcome reporting in clinical trials has been widely acknowledged, necessitating initiatives to enhance the quality of future research.

Numerical simulation of aerosolised medicine delivery through tracheostomy airways

The administration of inhaled antibiotics to patients with upper or lower respiratory infections is sometimes conducted via a tracheostomy airway. However, precise dosing via this route remains uncertain, especially in spontaneously breathing paediatric patients. 

Safety, tolerability, and pharmacokinetics of a 2 g subcutaneous dose of ceftriaxone as an alternative to intravenous delivery

Subcutaneous delivery of antibiotics is a practical alternative to intravenous administration. Ceftriaxone is commonly used for a variety of infections with limited data on the safety and pharmacokinetics of a 2 g subcutaneous dose. This was a prospective, self-controlled cross-over study in 20 stable inpatients receiving ceftriaxone for their infection. Following an intravenous dose, participants received a single dose of 2 g subcutaneous ceftriaxone, in 50 mL normal saline via gravity feed.