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This study was unable to demonstrate efficacy of 23vPPV in pregnancy against the co-primary outcomes of either all-cause infant ear disease.
The prevalence of parent-reported rOM was 26.8% (611/2280) and 5.5% (125/2280) for severe rOM in the Study.
Advances in understanding bacterial dynamics in the upper airway microbiome are driving development of microbiota-modifying therapies to prevent or treat disease
There is insufficient evidence available to determine whether these organisms are pathogens, commensals or contribute indirectly to the pathogenesis of OM
The effectiveness and safety profile of antiseptics in the treatment of chronic suppurative otitis media is uncertain
The longitudinal analyses found no evidence of increased (or decreased) long-term risk of ear infections in subsequent waves associated with attending a child care centre
Aboriginal children and children from lower socio-economic backgrounds were over-represented with OM-related hospitalizations but had fewer TTIs
To assess the relative effectiveness of topical versus systemic antibiotics for people with chronic suppurative otitis media
To assess the effects of aural toilet procedures for people with chronic suppurative otitis media
Researchers from The Kids Research Institute Australia have identified the main bacteria responsible for recurrent ear infections and repeat ear surgeries in children.