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Research

Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

We estimated age-sex-specific all-cause mortality using the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.

Research

A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development.

This publication is a systematic analysis of all Group A Streptococcus M protein variants, to assist in the development of a vaccine.

Research

The triple challenges associated with age-related comorbidities in Down syndrome

Major increases in the survival of people with Down syndrome during the last two generations have resulted in extended periods of adulthood requiring...

Research

Lower fructose intake may help protect against development of nonalcoholic fatty liver in adolescents with obesity

Although obesity is a major risk factor for nonalcoholic fatty liver (NAFL), not all individuals with obesity develop the condition, suggesting that other...

Research

Investigation of the Cross-National Equivalence of a Measurement of Early Child Development

The present study examined the psychometric properties of the domains of the 48-item EDI and the invariance of the measurement models of the domains of the...

Research

Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: A pilot study

To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican...

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Stillbirth and neonatal death rates across time: The influence of pregnancy terminations and birth defects in a Western Australian population-based cohort study

Changes in clinical practice related to pregnancy terminations have played a substantial role in shaping stillbirth and neonatal death rates in WA

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Patterns of depressive symptoms and social relating behaviors differ over time from other behavioral domains for young people with Down syndrome

People with intellectual disabilities are at a higher risk for experiencing behavioral, emotional, and psychiatric problems in comparison with the general...

Research

Can skin exposure to sunlight prevent liver inflammation?

Here we discuss how skin exposure to sunlight may suppress liver inflammation and the severity of NAFLD.

Research

Mechanisms of allergic disease - environmental and genetic determinants for the development of allergy

Environmental exposures including maternal inflammation, diet, nutrient balance, microbial colonization and toxin exposures can directly and indirectly...