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The present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric ARI.
Asthma is more common in childhood than in adulthood and is more correctly thought of as a syndrome than as a discrete condition.
Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.
There is increasing evidence that the functional state of the immune system at birth is predictive of the kinetics of immune maturation in early infancy.
the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories
Human perinatal life is characterized by a period of extraordinary change during which newborns encounter abundant environmental stimuli and exposure to potential pathogens. To meet such challenges, the neonatal immune system is equipped with unique functional characteristics that adapt to changing conditions as development progresses across the early years of life, but the molecular characteristics of such adaptations remain poorly understood.
Our findings provide new insight into the molecular mechanisms operative at baseline in the airway mucosa in atopic asthmatic with natural aeroallergen exposure
We identified new asthma loci, found new associations at loci implicated in the comorbidity of asthma plus hay fever and confirmed nine known loci.
This methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a...
New research links poor language to lack of Vitamin D in womb.