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Human Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations.

This is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children.

These findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children

We demonstrate that NOTCH3 is a regulator of MUC5AC production

The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children

These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed

Type 1 and 3 interferon response capacity appears strongly developmentally constrained at birth

Despite advances in asthma therapeutics, the burden remains highest in preschool children; therefore, it is critical to identify primary care tools that distinguish preschool children at high risk for burdensome disease for further evaluation.

Research question: Are asthma and allergies more common in adolescents conceived with assisted reproductive technologies (ART) compared with adolescents conceived without?

Excessive production, secretion, and retention of abnormal mucus is a pathological feature of many obstructive airways diseases including asthma. Azithromycin is an antibiotic that also possesses immunomodulatory and mucoregulatory activities, which may contribute to the clinical effectiveness of azithromycin in asthma.