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Research
T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide lengthT-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus.
Research
Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.This study describes the development and molecular characterization of a panel of patient-derived infant leukemia oncogene xenografts and their sensitivity...
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ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable.
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Acute hyperglycaemia does not alter nitric oxide-mediated microvascular function in the skin of adolescents with type 1 diabetesImpact of an acute bout of hyperglycaemia on nitric oxide (NO)-mediated microvascular function in the skin of adolescents with type 1 diabetes
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Reactive aggression and peer victimization from pre-kindergarten to first grade: accounting for hyperactivity and teacher-child conflictTeacher-child conflict in kindergarten predicted subsequent increases in victimization, reactive aggression, and hyperactivity
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The relationship between ambient ultraviolet radiation (UVR) and objectively measured personal UVR exposure dose is modified by season and latitudeSeason and latitude modify the relationship between ambient ultraviolet radiation and personal ultraviolet radiation exposure
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Soluble Glycoprotein VI Is Raised in the Plasma of Patients With Acute Ischemic Strokeschemic stroke induced by thrombosis may be triggered by atherosclerotic plaque rupture and collagen-induced platelet activation. Collagen induces...
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Variation over time in medical conditions and health service utilization of children with Down syndromeVariation over time in medical conditions and health service utilization of children with Down syndrome.
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Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different TrimestersA recent genome-wide association study identified variants near CCNL1/LEKR1 (rs900400) and in ADCY5 (rs9883204) to be associated with birth weight.
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High incidence of obesity co-morbidities in young children: A cross-sectional studyThe prevalence of overweight and obesity in children is a public health problem because of future morbidity.