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The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological markers of psychosis risk. We investigated baseline structural neuroimaging differences between individuals at CHR and healthy controls as well as between participants at CHR who later developed a psychotic disorder (CHR-PS+) and those who did not (CHR-PS-).

Serotonin (5-HT) is widely implicated as a key neurotransmitter relevant to a range of psychiatric disorders and psychological processes. The role of central nervous 5-HT function underlying these processes can be examined through serotonergic challenge methodologies.

Wearable technologies impact upon sexual activity and this influences the decision to adopt the technology

Misgendering within the health care system can significantly affect the mental and physical health of transgender individuals

The current article outlines how individuals with fetal alcohol spectrum disorder may experience inequities within the justice system

In this population-based cohort that included 2,084 children with autism aged ≤6 years, over one-third met the criteria for motor difficulties

In this article, we examine the utility of a transdiagnostic, dimensional approach to very early identification and intervention for infants at risk of neurodevelopmental disorders

Sport-based interventions could be an opportunity to provide intervention to individuals recovering from their first psychotic episode

The aim of the study was to develop and validate an individualized, clinically based prognostic model for forecasting transition to psychosis from a CHR-P stage

ADHD patients showed substantially diminished intrinsic coupling for 7 connections and increased coupling for 4 connections