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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia PathogenesisHere we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia
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A Comparison of the Motor Skills of Young People in a Youth Detention Centre with Diagnosed Fetal Alcohol Spectrum Disorder and Prenatal Alcohol ExposureVisual motor integration and handwriting skills were often impaired in this population of young people in a youth detention centre
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Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized MedicineIn this Review, we consolidate the latest updates in the development of primary epithelial cellular model systems relevant for cystic fibrosis
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Immunogenicity and Safety of Monovalent Acellular Pertussis Vaccine at Birth: A Randomized Clinical TrialThe monovalent acellular pertussis vaccine is immunogenic and safe in neonates
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Trial refresh: A case for an adaptive platform trial for pulmonary exacerbations of cystic fibrosisThis review will discuss the necessary steps required for a Bayesian adaptive platform trial to optimize treatment of pulmonary exacerbations of cystic fibrosis
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Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection studyWe review the Group A Streptococcus Human infection studies and present the study protocol for a dose-ranging inpatient study in healthy adults
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Discrete choice experiment to evaluate preferences of patients with cystic fibrosis among alternative treatment-related health outcomes: A protocolThe aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes
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Preventive medicine for person, place, and planet: Revisiting the concept of high-level wellness in the planetary health paradigmHere, we discuss the relevance of planetary health in the era of personalized medicine, gross environmental concerns, and a crisis of non-communicable diseases
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Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early lifeIntra-breath forced oscillation technique can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life
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Exposure to Ultraviolet Radiation in the Modulation of Human DiseasesThis review focuses primarily on the beneficial effects for human health of exposure to ultraviolet radiation