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Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.
The authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by...
We tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype.
The purpose of this Review was to give an overview of the recent research into whether a lack of vitamin D contributes to the development of atopy and asthma...
The co-exposure responses in the Th2high BN incorporated type I interferon/Th1, alternative macrophage activation/Th2 and Th17 signatures
To complement early allergic sensitization, monitoring NPM composition may enable early detection and intervention in high-risk children
There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years
Australian infants who received whole-cell pertussis vaccines were less likely to be diagnosed with food allergy in childhood
Recent birth cohort studies showed a significant interaction between cat ownership at birth and mutations in FLG on the development of early‐onset atopic dermatitis
In asthma, a significant portion of the interaction between genetics and environment occurs through microbiota. The proposed mechanisms behind this interaction are complex and at times contradictory. This review covers recent developments in our understanding of this interaction: the "microbial hypothesis" and the "farm effect"; the role of endotoxin and genetic variation in pattern recognition systems; the interaction with allergen exposure; the additional involvement of host gut and airway microbiota; the role of viral respiratory infections in interaction with the 17q21 and CDHR3 genetic loci; and the importance of in utero and early-life timing of exposures.