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Vaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.
Group A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing).
To date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological...
We present further data on vaccine efficacy (VE) against HPV-16/18 in the total vaccinated cohort including women who may have been exposed to HPV-16/18...
There is a lack of data on the out-of-hospital burden of acute lower respiratory infections (ALRI) in developed countries.
Human rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children...
Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator.
Globally, ARF and RHD cause more than a quarter of a million deaths and substantial disability each year.
Neisseria meningitidis is a leading cause of meningitis and septicaemia, but a broadly-protective vaccine against endemic serogroup B disease is not licensed...
Our study will be the first to assess vaccine efficacy targeting H. influenzae in children with recurrent PBB, CSLD and bronchiectasis.