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Investigations into the role of ST2 in acute asthma in childrenThis study investigated the potential role of ST2 in children with acute asthma.
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Siblings of children with disabilities: challenges and opportunitiesSiblings of children with disabilities: challenges and opportunities
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Rio Tinto Child Health Partnership Final ReportIn 2002, the Founding Director of The Kids for Child Health Research, Professor Fiona Stanley, approached Rio Tinto Ltd about the possibility...
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Investigating genotype-phenotype relationships in Rett syndrome using an international data setThis study uses data from a large international database, InterRett, to examine genotype-phenotype relationships and compares these with previous findings in...
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Late language emergence at 24 months: an epidemiological study of prevalence, predictors, and covariatesThe primary objectives of this study were to determine the prevalence of late language emergence (LLE) and to investigate the predictive status of maternal...
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Diverging trends for lower respiratory infections in non-Aboriginal and Aboriginal childrenTo investigate temporal trends in admission rates for acute lower respiratory infections (ALRI) in a total population birth cohort of non-Aboriginal and...
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Vaccinating young adults against HPV: the importance of understanding health decision-making and behaviourVaccination of young teenage females against human papillomavirus (HPV) with a newly licenced quadrivalent vaccine designed to prevent cervical cancer and...
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New meningococcal strains bring increased risk in WAA new study has confirmed the changing pattern of meningococcal disease in Western Australia.
Research
Ion channel modulator DPI-201-106 significantly enhances antitumor activity of DNA damage response inhibitors in glioblastomaGlioblastoma, a lethal high-grade glioma, has not seen improvements in clinical outcomes in nearly 30 years. Ion channels are increasingly associated with tumorigenesis, and there are hundreds of brain-penetrant drugs that inhibit ion channels, representing an untapped therapeutic resource. The aim of this exploratory drug study was to screen an ion channel drug library against patient-derived glioblastoma cells to identify new treatments for brain cancer.
Research
Systematic Review of Household Transmission of Strep A: A Potential Site for Prevention That Has Eluded AttentionAlthough Streptococcus pyogenes (Strep A) is the sixth-most common infectious disease globally, its transmission within the household remains an understudied driver of infection. We undertook a systematic review to better understand the transmission of Strep A among people within the home, while highlighting opportunities for prevention.