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Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposityEnvironmental factors including excessive caloric intake lead to disordered lipid metabolism and fatty liver disease.
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Evaluation of a new measure of mood intolerance, the Tolerance of Mood States Scale (TOMS)This research aimed to (i) validate a new measure of mood intolerance, the Tolerance of Mood States (TOMS) scale, and (ii) to examine associations between...
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Sex dimorphism in the relation between early adiposity and cardiometabolic risk in adolescentsBirth weight and childhood adiposity are associated with subsequent cardiovascular risk. We investigated the associations between metabolic clusters in young...
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Umbilical venous blood flow and its measurement in the human fetusIn this review, we evaluate the published methodologies to describe a noninvasive technique for the quantitative assessment of umbilical venous blood flow in...
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Neonatal skin: barrier, immunity and infection prevention in the NICUThe neonatal skin is central to early survival and immune development. Far from being a passive mechanical barrier, it integrates physical, chemical, and microbial defences that together protect the infant in the immediate postnatal period. In preterm infants, structural immaturity, reduced antimicrobial capacity, and altered microbial colonisation confer heightened vulnerability to infection and inflammation.
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DeepEGFR a graph neural network for bioactivity classification of EGFR inhibitorsEpidermal Growth Factor Receptor (EGFR) plays a critical role in the development of several cancers. Thus, modulation/inhibition of EGFR activity is an appealing target of developing novel cancer therapeutics.
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanomaA range of microbiota species correlate with improved cancer outcomes in patients and confer protection in pre-clinical mouse models. Here, we examined how microbiota regulate CD8+ T cell immunity against melanoma. Spontaneous control of cutaneous melanoma in mice correlated with metabolic pathways required for microbial synthesis of short-chain fatty acids (SCFAs) shared between several microbiota species.
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Skin infections flying under the radarThe Kids Research Institute Australia researchers have confirmed that skin infections in many Aboriginal children across northern Western Australia are going unrecognised.
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Epidural insertion height for ureteric reimplant surgery; does location matter?The caudal catheter technique was superior at reducing pain interventions, particularly bladder spasm interventions
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A fine balance and a shared learning journey: Exploring healthcare engagement through the experiences of youth with Neuromuscular DisordersExplored Youth with Neuromuscular Disorders perceptions of health, health behaviors and healthcare engagement