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Research
Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemiaBiological changes associated with T-ALL relapse and resistance are stochastic and highly individual
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Hospital admission for infection during early childhood influences developmental vulnerabilities at age 5 yearsThis study demonstrates a pervasive effect of early life infections that require hospital admission on multiple aspects of early child development
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Adolescent and young adult medicine in Australia and New Zealand: towards specialist accreditationThe RACP is advancing a three-tier strategy to build greater specialist capacity and sustain leadership in adolescent and young adult medicine
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Asymptomatic CMV infections in long-term renal transplant recipients are associated with the loss of FcRγ from LIR-1+ NK cellsCMV can be reactivated in symptom-free renal transplant recipients, affecting the phenotypic, and functional profiles of NK cells
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Helicobacter pylori overcomes natural immunity in repeated infectionsHelicobacter pylori infection does not promote an immune response protective against future reinfection
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Mental disorders in Australian 4- to 17- year olds: Parent-reported need for helpMany children and adolescents meeting Diagnostic and Statistical Manual of Mental Disorders, 4th edition criteria for mental disorders have a completely unmet need for help, especially those with conduct disorders.
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Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infectionDysfunction of T follicular-helper cells is a possible cause of impaired germinal centre and IgG antibody responses in individuals with HIV
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Exploration of the Performance of a Hybrid Closed Loop Insulin Delivery Algorithm That Includes Insulin Delivery Limits Designed to Protect Against HypoglycemiaThe algorithm that was tested against moderate exercise and an overreading glucose sensor performed well in terms of hypoglycemia avoidance
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Key paediatric messages from the 2016 European respiratory society international congressHighlight of some of the most interesting abstracts presented at the 2016 ERS International Congress, which was held in London
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Kids in Communities Study (KiCS) study protocol: A cross-sectional mixed-methods approach to measuring community-level factors influencing early child development in AustraliaThe Kids in Communities Study will test and investigate community-level influences on child development across Australia