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Research

If you think you can do it, that's confidence: If you do it that's competence-Where are we in pediatric anesthesia?

Should we be practicing new procedures on children under our care in the absence of formal supervision, teaching, and assessment that prove we are competent to do so

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Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection

Dysfunction of T follicular-helper cells is a possible cause of impaired germinal centre and IgG antibody responses in individuals with HIV

Research

ERS technical standard on bronchial challenge testing: General considerations and performance of methacholine challenge tests

This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test.

Research

Early childhood development of boys with genital anomalies

We found no increased risk of poor development among boys with hypospadias or undescended testis

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CAGEd-oPOSSUM: motif enrichment analysis from CAGE-derived TSSs

CAGEd-oPOSSUM can identify transcription factors that act as key regulators of genes involved in specific mammalian cell and tissue types

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Key paediatric messages from the 2016 European respiratory society international congress

Highlight of some of the most interesting abstracts presented at the 2016 ERS International Congress, which was held in London

Research

The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1

Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1

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Hospital admission for infection during early childhood influences developmental vulnerabilities at age 5 years

This study demonstrates a pervasive effect of early life infections that require hospital admission on multiple aspects of early child development

Research

European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia

Guideline to provide evidence-based recommendations on diagnostic testing for primary ciliary dyskinesia

Research

Asymptomatic CMV infections in long-term renal transplant recipients are associated with the loss of FcRγ from LIR-1+ NK cells

CMV can be reactivated in symptom-free renal transplant recipients, affecting the phenotypic, and functional profiles of NK cells