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News & Events

Latest RSV results pave way for world-first vaccine

The Kids Research Institute Australia researchers leading the Western Australian site of a global respiratory syncytial virus (RSV) study can now fine-tune development of a world-first vaccine for pregnant mothers.

News & Events

COVID-19 information

The situation with COVID-19 is constantly evolving, and there is an extraordinary amount of information circulating which can be both overwhelming and difficult to navigate.

News & Events

Perth researchers one step closer to wiping out childhood ear infections

Researchers from The Kids Research Institute Australia have identified the main bacteria responsible for recurrent ear infections and repeat ear surgeries in children.

News & Events

Landmark Australian influenza collaboration finalist for Eureka Prize

Infectious disease researchers who used a decade of scientific evidence to advocate for a nationwide childhood influenza immunisation policy have earned a finalist position at the country’s most prestigious science awards – the Australian Museum Eureka Prizes.

News & Events

The Kids ear health researcher takes out top science prize at 40Under40 Awards

Dr Chris Brennan-Jones received the Woodside STEM Award for Excellence in Science at the prestigious 40Under40 Awards.

News & Events

The Kids Research Institute Australia researcher wins Eureka Prize for Emerging Leader in Science

Paediatric infectious disease expert and clinician-scientist Associate Professor Asha Bowen has been named as the Emerging Leader in Science at the country’s most prestigious science awards – the Australian Museum Eureka Prizes.

News & Events

‘Mama’ deb’s dedication to saving children in Papua New Guinea

Children living in Papua New Guinea have good reason to call Clinical Associate Professor Deborah Lehmann ‘Mama Deb’.

Research

A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study

Streptococcus pyogenes is a leading cause of infection-related morbidity and mortality. A reinvigorated vaccine development effort calls for new clinically relevant human S pyogenes experimental infection models to support proof of concept evaluation of candidate vaccines. We describe the initial Controlled Human Infection for Vaccination Against S pyogenes (CHIVAS-M75) study, in which we aimed to identify a dose of emm75 S pyogenes that causes acute pharyngitis in at least 60% of volunteers when applied to the pharynx by swab.

Research

Clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation (CASSETTE)-an open-labelled pilot randomized controlled trial

Combination antibiotic therapy with an antitoxin agent, such as clindamycin, is included in some guidelines for severe, toxin-mediated Staphylococcus aureus infections. The evidence to support this practice is currently limited to in vitro, animal and observational human case-series data, with no previous randomized controlled trials (RCTs).

Research

Otitis media guidelines for Australian Aboriginal and Torres Strait Islander children: summary of recommendations

The 2001 Recommendations for clinical care guidelines on the management of otitis media in Aboriginal and Torres Islander populations were revised in 2010. This 2020 update by the Centre of Research Excellence in Ear and Hearing Health of Aboriginal and Torres Strait Islander Children used for the first time the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.