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Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised childrenWe aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.
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Use of the Dietary Guideline Index to assess cardiometabolic risk in adolescentsThe long-term adherence to the dietary guidelines has not been evaluated against emergence of cardiometabolic risks in adolescents with increasing rates of...
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Intellectual disability: Population-based estimates of the proportion attributable to maternal alcohol use disorder during pregnancyThe aim of this study was to examine the association between maternal alcohol use disorder and intellectual disability in children.
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The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study.While previous studies have found a link between testosterone levels in amniotic fluid and autistic-like traits, a similar relationship has not been found...
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Tertiary paediatric refugee health clinic in Western Australia: Analysis of the first 1026 childrenThe aim of this study is to describe the epidemiology of common conditions in resettled paediatric refugees attending a tertiary multidisciplinary RHC.
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UV Irradiation of Skin Regulates a Murine Model of Multiple Sclerosis.The prevalence of multiple sclerosis follows a latitude gradient, with increased disease at higher latitudes.
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MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis.
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Clinical cardiovascular risk during young adulthood in offspring of hypertensive pregnancies:Offspring of hypertensive pregnancies have increased cardiovascular risk factors during childhood.
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Use of data linkage to investigate the aetiology of acute lower respiratory infection hospitalisations in childrenThe aim was to document the aetiology of acute lower respiratory infection (ALRI) hospitalisations in Western Australian children
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Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated ComplicationWe undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...
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Two methods for engaging with the community in setting priorities for child health research: Who engages?The Western Australian Telethon Kids Institute Participation Program employs a range of methods for fostering active involvement of community members in its...
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Childhood Hospitalisation with Infection and Cardiovascular Disease in Early-Mid Adulthood: A Longitudinal Population-Based StudyWe investigated whether childhood infection-related hospitalisation (IRH, a marker of severity) was associated with subsequent adult CVD hospitalisation.
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Novel CT domain-encoding splice forms of CTGF/CCN2 are expressed in B-lineage acute lymphoblastic leukaemiaConnective tissue growth factor (CTGF/CCN2) has been shown previously to be aberrantly expressed in a high proportion of paediatric precursor B cell acute...
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Cardiac autonomic dysfunction is associated with high-risk albumin-to-creatinine ratio in young adolescents with type 1 diabetes in AdDITThis study examined the association between cardiac autonomic dysfunction and high albumin-to-creatinine ratio (ACR) in adolescents with type 1 diabetes.
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The aggregation of early-onset melanoma in young Western Australian familiesResults indicated a strong familial basis of melanoma, with the higher than expected hazard ratio observed likely to reflect early-age at onset cases in this...