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Research
Potential impact of a maternal vaccine for RSV: A mathematical modelling studyRespiratory syncytial virus is a major cause of respiratory morbidity and one of the main causes of hospitalisation in young children.
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Maternal alcohol use disorder and subsequent child protection contact: A record-linkage population cohort studyWe examined the relationship between a maternal alcohol-use diagnosis, and the timing of diagnosis, and child protection outcomes in a Western Australian population cohort.
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REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegiaCongenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial.
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Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from MozambiqueWe investigated IL-4, IL-13, and IL-4Rα polymorphisms and their impact on measles IgG responses and measles vaccine failure, in two separate cohort.
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Comparative analyses of whole genome sequences of Leishmania infantum isolates from humans and dogs in northeastern BrazilOverall the analyses do not suggest individual sequence variants account for differences in clinical outcome or adaptation to different hosts.
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Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping"
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Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitorWe report on 3 children treated with vismodegib who developed widespread growth plate fusions that persist long after cessation of therapy.
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Dose-Banding of Intravenous Piperacillin-Tazobactam in Pediatric Surgical InpatientsDosing errors are the most commonly reported medication error in children. Dosing is often prescribed per weight or based on body area.
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An integrated expression atlas of miRNAs and their promoters in human and mouseWe provided a broad atlas of miRNA expression and promoters in primary mammalian cells, establishing a foundation for detailed analysis of miRNA.
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Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination the Western Australian Aboriginal populationThe PCV7 was introduced to prevent IPD in WA Aboriginal people in 2001 to a lesser extent in older people.