Search
The airway epithelium of both children and adults with asthma is relatively undifferentiated characterized by a significantly increased proportion of...
Our experiments provide proof of principle for the use of PSC-derived respiratory epithelial cells in the study of cell-virus interactions.
Chest computed tomography (CT) is the gold standard for demonstrating cystic fibrosis (CF) airway disease. However, there are no standardized outcome...
Airway inflammation and infection are present from early in life, often before children are symptomatic.
Chronic airway injury and dysregulated repair programs are evident in airway epithelium obtained from patients with bronchiolitis obliterans syndrome
Our work has identified a clinically relevant host-derived factor that may participate in shaping early events in the aetiology of CF respiratory disease
Our data suggest that FRC PC-CTs are less sensitive than TLC PC-CTs and that FB-CTs have similar sensitivity to PC-CTs in detecting lung disease
We demonstrate that NOTCH3 is a regulator of MUC5AC production
This study found rhinovirus infection drives necrotic cell death in cystic fibrosis airway epithelial cells
Here we show that antibacterial activity of 4-hydroxy-2-heptylquinoline against Vibrionaceae is species-specific