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Synthesized findings demonstrate that people with intellectual disability, who live in community or residential settings, may fall more frequently, and at a younger age

Research

Findings were mixed, with support both for negative and for positive associations of central nervous 5-HT function with aggression in children and adolescents

Research

In adult and elderly participants, the full-dose aH5N1c vaccine formulation was well tolerated and met US and European licensure criteria for pandemic vaccines

Research

The findings indicated that in spite of continued promotion of the AIFG over the past ten years achieving the around six months guideline is challenging

Research

Birth prevalence of CP declined. Encouragingly, the percentage of children with CP whose disability was moderate to severe also decreased

Research

We investigated the influence of brain serotonin modulation and MAOA genotype on functional amygdala connectivity during aggressive behavior

Research

In this concept paper, we discuss multiomic approaches to studying immune dysregulation and highlight some of the challenges and opportunities

Research

The immunological mechanisms that contribute to multiple sclerosis (MS) differ between males and females. Females are 2-3 times more likely to develop MS compared to males, however the reason for this discrepancy is unknown. Once MS is established, there is a more inflammatory yet milder form of disease in females whereas males generally suffer from more severe disease and faster progression, neural degradation, and disability.

Research

Autism spectrum disorders are complex, with a strong genetic basis. Genetic research in autism spectrum disorders is limited by the fact that these disorders are largely heterogeneous so that patients are variable in their clinical presentations. To address this limitation, we investigated the genetics of individual dimensions of the autism spectrum disorder phenotypes, or autistic-like traits. These autistic-like traits are continuous variations in autistic behaviours that occur in the general population.

Research

To determine whether serum neurofilament light chain (sNfL) levels are suppressed in patients with the clinically isolated syndrome (CIS) following narrowband ultraviolet B phototherapy (UVB-PT).