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Research

β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating Peptides

The β-lactamase assays provide compatible tools for functional characterization of CPP activity and the delivery of biological cargos into cells

Research

Large-Scale Structural Variation Detection in Subterranean Clover Subtypes Using Optical Mapping

The accuracy of structural variations detection by Bionano optical mapping is highly dependent on the quality of reference genomes and the density of selected nickases

Research

Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions

This is the first report examining the role of different rhinovirus species in ARIs in children admitted to a tertiary PICU

Research

Vitamin D supplementation of initially vitamin D-deficient mice diminishes lung inflammation with limited effects on pulmonary epithelial integrity

In disease settings, vitamin D may be important for maintaining optimal lung epithelial integrity and suppressing inflammation, but less is known of its effects prior to disease onset.

Research

Duration of general anaesthetic exposure in early childhood and long-term language and cognitive ability

Anaesthetic dose causing toxicity in animals has been evaluated, but the relationship between duration of VA exposure and development in children remains vague.

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Hypermasculinised facial morphology in boys and girls with Autism Spectrum Disorder and its association with symptomatology

This is the first study demonstrating facial hypermasculinisation in ASD and its relationship to social-communication difficulties in prepubescent children

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Parents’ interest in their child's education and children's outcomes in adolescence and adulthood: Does gender matter?

We found no evidence of gender-specific effects for the outcomes of academic achievement, educational expectations or educational attainment in adulthood.

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PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

Our results reveal long-lasting changes to progenitor cells of monocytes/macrophages by a 2-hour dimethyl PGE2 pulse that, in turn, limits the migration of their daughter cells to chemoattractants and inflammatory mediators.

Research

A longitudinal analysis of the influence of the neighborhood environment on recreational walking within the neighborhood: Results from RESIDE

evidence of the positive impact of well-connected neighborhoods and access to local parks of varying sizes on local residents’ recreational walking and health

Research

A randomized controlled evaluation of a secondary school mindfulness program for early adolescents: Do we have the recipe right yet?

Further research is required to identify the optimal age, content and length of mindfulness programs for adolescents in universal prevention settings.